abstract：:Tolvaptan is a highly selective and orally effective arginine vasopressin V2 receptor antagonist, and is potentially useful for the treatment of heart failure (HF) patients. However, the renoprotective effect of long-term tolvaptan therapy and its underlying mechanisms remain unknown. We evaluated the effects of chron...

journal_title：International heart journal

authors： Ishikawa M,Kobayashi N,Sugiyama F,Onoda S,Ishimitsu T

更新日期：2013-01-01 00:00:00

abstract：:Several recent studies have suggested that arterial stiffness parameters such as peripheral pulse pressure (PPP), central blood pressure (CBP), and pulse wave velocity (PWV) are more accurate markers than brachial blood pressure for prediction of cardiovascular (CV) events. However, it remains unknown which arterial s...

journal_title：International heart journal

authors： Ishisone T,Koeda Y,Tanaka F,Sato K,Nagano M,Nakamura M

更新日期：2013-01-01 00:00:00

abstract：:Marfan syndrome (MFS) is an inherited connective tissue disorder mainly caused by the fibrillin-1 mutation. Deficient fibrillin-1 is thought to result in the failed sequestration of transforming growth factor β (TGFβ) and subsequent activation of the TGFβ signaling pathway, suggesting that the circulating TGFβ level m...

journal_title：International heart journal

authors： Ogawa N,Imai Y,Nishimura H,Kato M,Takeda N,Nawata K,Taketani T,Morota T,Takamoto S,Nagai R,Hirata Y

更新日期：2013-01-01 00:00:00

abstract：:Percutaneous balloon mitral valvoplasty (PBMV) has become the treatment of choice for severe pliable rheumatic mitral stenosis. The multi-track system is a recent variation of the double-balloon technique and is easier owing to the use of a monorail balloon and a simple, single-guidewire approach. In the present study...

journal_title：International heart journal

authors： Sakr SA,Ramadan MM,Osama M

更新日期：2013-01-01 00:00:00

abstract：:Renal injury is an important factor for worsening outcome in acute decompensated heart failure (ADHF). An 81-year-old woman was admitted due to ADHF with dyspnea and mild peripheral edema. The patient was managed with intravenous administration of atrial natriuretic peptide (ANP) at a dose of 0.0125 μg/kg/minute, whic...

journal_title：International heart journal

authors： Kamiya M,Sato N,Akiya M,Okazaki H,Takahashi Y,Mizuno K

更新日期：2013-01-01 00:00:00

abstract：:Prevalent atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM) represents an important issue with regard to stroke events caused by embolization and is associated with high mortality. Increased epicardial adipose tissue (EAT), which shows high metabolic activity, can locally influence the activi...

journal_title：International heart journal

authors： Muhib S,Fujino T,Sato N,Hasebe N

更新日期：2013-01-01 00:00:00

abstract：:Cardiac output (CO) is often desirable for assessing the hemodynamic condition of a patient, especially in critically ill cardiac patients. Various noninvasive methods are available for this purpose. Inert gas rebreathing (IGR) and 2D-Doppler echocardiography methods have been validated. Based on the relationship betw...

journal_title：International heart journal

authors： Raissuni Z,Zores F,Henriet O,Dallest S,Roul G

更新日期：2013-01-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection remains a major problem in recipients with heart transplantation (HTx), because it may play a significant role in the development of cardiac allograft vasculopathy, which is one of the major causes of death after HTx. Valganciclovir (VGC) is effective for the treatment of CMV infection,...

journal_title：International heart journal

authors： Imamura T,Shiga T,Kinugawa K,Kato N,Endo M,Inaba T,Maki H,Hatano M,Yao A,Hirata Y,Nagai R

更新日期：2012-01-01 00:00:00

abstract：:Left ventricular outflow tract obstruction (LVOTO) is commonly observed in patients with hypertrophic cardiomyopathy (HCM) or left ventricular hypertrophy (LVH). While some patients develop LVOTO at rest, it can also be provoked by physical exertion, and hence termed latent LVOTO (L-LVOTO). Recent reports demonstrated...

journal_title：International heart journal

authors： Semba H,Sawada H,Uejima T,Takeda N,Soma K,Abe H,Yamashita T,Nagai R

更新日期：2012-01-01 00:00:00

abstract：:Transradial percutaneous coronary intervention (PCI), which is less invasive than transfemoral PCI, may facilitate early rehabilitation of patients with acute myocardial infarction (AMI). The aim of our study was to investigate whether transradial PCI is associated with a shorter coronary care unit (CCU) stay in very ...

journal_title：International heart journal

authors： Jinnouchi H,Sakakura K,Wada H,Kubo N,Sugawara Y,Nakamura T,Funayama H,Ako J,Momomura S

更新日期：2012-01-01 00:00:00

abstract：:It has been reported that K-ATP channel openers have a cardioprotective effect in acute ischemia as a pharmacological preconditioning effect. In the present study, the chronic effects of clinical K-ATP channel openers, ie, nicorandil (Nic) and mexiletine (Mex), on cardiac function were evaluated in a rat model of expe...

journal_title：International heart journal

authors： Niwano S,Hirasawa S,Niwano H,Sasaki S,Masuda R,Sato K,Masuda T,Izumi T

更新日期：2012-01-01 00:00:00

abstract：:The efficacy of heart failure (HF) management programs is compromised by the challenge of early identification of patients at imminent risk. Segmental multifrequency bioelectrical impedance analysis can generate an "edema index" (EI) as a surrogate for the body fluid status. In this study, we tested whether integratio...

journal_title：International heart journal

authors： Liu MH,Wang CH,Huang YY,Tung TH,Lee CM,Yang NI,Wang JS,Kuo LT,Cherng WJ

更新日期：2012-01-01 00:00:00

abstract：:Mitochondrial disorders comprise a heterogeneous group of diseases with multisystem involvement including myocardium. Most cases of mitochondrial cardiomyopathy are associated with myopathy and encephalopathy and are generally present in infancy or childhood. The disease often exhibits a rapid downward course with dea...

journal_title：International heart journal

authors： Palecek T,Tesarova M,Kuchynka P,Dytrych V,Elleder M,Hulkova H,Hansikova H,Honzik T,Zeman J,Linhart A

更新日期：2012-01-01 00:00:00

abstract：:Mitral and aortic valve regurgitation is commonly found in osteogenesis imperfecta (OI) patients, however, little is known about the myocardial involvement in this disorder. An 82-year-old man with OI developed heart failure and was admitted to our hospital. Echocardiogram revealed severe mitral regurgitation without ...

journal_title：International heart journal

authors： Soma K,Abe H,Takeda N,Shintani Y,Takazawa Y,Kojima T,Fujiu K,Semba H,Yamashita H,Hirata Y,Fukayama M,Nagai R

更新日期：2012-01-01 00:00:00

abstract：:The purpose of this study was to investigate the precise pattern of stroke volume (SV) response during exercise in patients with chronic heart failure (CHF) compared with age-matched controls. Fourteen patients with CHF and 7 controls performed symptom-limited bicycle exercise testing with respiratory gas exchange mea...

journal_title：International heart journal

authors： Fukuda T,Matsumoto A,Kurano M,Takano H,Iida H,Morita T,Yamashita H,Hirata Y,Nagai R,Nakajima T

更新日期：2012-01-01 00:00:00

abstract：:The relationship between mild-to-moderate renal dysfunction and cardiac diastolic dysfunction and cardiac events in patients with nonischemic dilated cardiomyopathy (NDCM) has not been fully elucidated. The aim of this study was to investigate the relationship between renal and cardiac function, as well as clinical ou...

journal_title：International heart journal

authors： Ohshima K,Hirashiki A,Cheng XW,Hayashi M,Hayashi D,Okumura T,Sakakibara M,Funahashi H,Ohshima S,Murohara T

更新日期：2011-01-01 00:00:00

abstract：:High mobility group box 1 (HMGB1), which has properties similar to those of proinflammatory cytokines, is released from activated immune cells and necrotic cells. It is known that cardiopulmonary bypass (CPB) induces systemic inflammation and aortic cross-clamping induces myocardial ischemia. This study was conducted ...

journal_title：International heart journal

authors： Haque A,Kunimoto F,Narahara H,Okawa M,Hinohara H,Kurabayashi M,Saito S

更新日期：2011-01-01 00:00:00

abstract：:The chronic use of bosentan has been reported to reduce the plasma concentration of sildenafil. However, it remains unclear how sildenafil exerts the effect at reduced concentrations in pulmonary arterial hypertension (PAH) patients chronically treated with bosentan.We examined the hemodynamic effects of sildenafil (5...

journal_title：International heart journal

authors： Hatano M,Yao A,Kinugawa K,Hirata Y,Nagai R

更新日期：2011-01-01 00:00:00

abstract：:HMG-CoA reductase inhibitors (statins) reduce major adverse cardiac events (MACE) and mortality in patients with acute coronary syndrome. We investigated whether early statin therapy would be effective at reducing MACE in patients with acute myocardial infarction (AMI).A total of 1,159 patients were analyzed. They wer...

journal_title：International heart journal

authors： Kim MC,Ahn Y,Cho KH,Lee MG,Ko JS,Park KH,Sim DS,Yoon NS,Yoon HJ,Kim KH,Hong YJ,Park HW,Kim JH,Jeong MH,Cho JG,Park JC,Kang JC

更新日期：2011-01-01 00:00:00

abstract：:Although pressure-overload right ventricular hypertrophy is a long-term risk in some congenital heart diseases such as tetralogy of Fallot, how it develops is unclear. The aim of this study was to investigate the mechanism of development of this right ventricular heart failure.Pulmonary artery banding in 10-day-old ra...

journal_title：International heart journal

authors： Minegishi S,Kitahori K,Murakami A,Ono M

更新日期：2011-01-01 00:00:00

abstract：:Five patients who had had previous cardiac operations underwent minimally invasive beating heart mitral valve operations via a right minithoracotomy between November 2006 and February 2009. The mean age was 64 ± 10 years and 4 were female. Under general anesthesia with single-lumen ventilation, cardiopulmonary bypass ...

journal_title：International heart journal

authors： Kitamura T,Stuklis RG,Edwards J

更新日期：2011-01-01 00:00:00

abstract：:Proinflammatory cytokine responses might occur in elderly individuals with cardiovascular (CV) disease, cerebro-vascular (CVA) disease, and/or pulmonary disease (PD). Spiritual activation is an important coping mechanism, since psychiatric depression is an important risk factor for these individuals. Thirty-three very...

journal_title：International heart journal

authors： Kurita A,Takase B,Shinagawa N,Kodani E,Okada K,Iwahara S,Kusama Y,Atarashi H

更新日期：2011-01-01 00:00:00

abstract：:The aim of the present study was to determine whether symptoms of atrial fibrillation (AF) differ between patients with and without subsequent permanent AF. Sixty-four patients (68 +/- 10 years old, 45 males) were recruited. AF follow-up was started at the age of 61 +/- 10 years and accomplished in a median period of ...

journal_title：International heart journal

authors： Kawara T,Narumi J,Hirao K,Kasuya K,Kawabata M,Tojo N,Isobe M,Matsuura M

更新日期：2010-07-01 00:00:00

abstract：:Steam pop and intramural charring have been reported during cooled-tip radiofrequency catheter ablation (RFCA). We studied the feasibility of temperature-controlled cooled-tip RFCA in the canine heart.An internally cooled ablation catheter was inserted into the left ventricle. A custom-made radiofrequency (RF) generat...

journal_title：International heart journal

authors： Watanabe I,Nuo M,Okumura Y,Ohkubo K,Ashino S,Kofune M,Kofune T,Nakai T,Kasamaki Y,Hirayama A

更新日期：2010-05-01 00:00:00

abstract：:The transradial approach for coronary diagnostic and therapeutic interventions is a well-established, safe, and effective technique that has shown a success rate comparable to that of the transfemoral approach for chronic total occlusion (CTO) with less access site complications. Recently, the transulnar approach was ...

journal_title：International heart journal

authors： Hussein H,Gan HW,Fang HY,Wu CJ

更新日期：2010-03-01 00:00:00

abstract：:Bilirubin has been considered an antioxidant, with capacity to remove reactive species of oxygen. Studies have suggested that an increased bilirubin level promotes protection against atherosclerosis. The case group was composed of 100 patients with coronary artery disease and the control group 100 patients with normal...

journal_title：International heart journal

authors： Ghem C,Sarmento-Leite RE,de Quadros AS,Rossetto S,Gottschall CA

更新日期：2010-03-01 00:00:00

abstract：:Increased QT dispersion (QTd) is a marker of myocardial electrical instability and predicts ventricular arrhythmias and sudden cardiac death. Exercise training (ET) has been shown to reduce both QTd and cardiovascular mortality in various populations. Patients with metabolic syndrome (MS) have been shown to have incre...

journal_title：International heart journal

authors： Guiraud T,Gayda M,Curnier D,Juneau M,Talajic M,Fortier A,Nigam A

更新日期：2010-01-01 00:00:00

abstract：:Despite wide interindividual variability in response to clopidogrel, platelet P2Y(12) ADP receptor inhibition in Japanese patients has not been fully studied using specific methodology. This study compared platelet P2Y(12) ADP receptor inhibition during treatment with clopidogrel versus clopidogrel plus cilostazol in ...

journal_title：International heart journal

authors： Fu Q,Yokoyama N,Takada K,Ishikawa S,Isshiki T

更新日期：2010-01-01 00:00:00

abstract：:Most previous studies have examined the effects of antihypertensive drugs in hypertensive animals for only a few months, and little information has been provided as to the protective effects of lifetime antihypertensive medication against cardiovascular organ injury. In this study, spontaneously hypertensive rats (SHR...

journal_title：International heart journal

authors： Ishimitsu T,Honda T,Ohno E,Furukata S,Sudo Y,Nakano N,Takahashi T,Ono H,Matsuoka H

更新日期：2010-01-01 00:00:00

abstract：:Same-day discharge transradial percutaneous coronary intervention (TRI) has been reported to be safe and feasible in Western countries. However, Asia has not produced any reports related to this matter. The present study explored the safety and feasibility of patients with indications for TR coronary angiography and a...

journal_title：International heart journal

authors： Chung WJ,Fang HY,Tsai TH,Yang CH,Chen CJ,Chen SM,Cheng CI,Fang CY,Hsieh YK,Hang CL,Yip HK,Wu CJ

更新日期：2010-01-01 00:00:00

abstract：:Statins improve left ventricular (LV) remodeling in spontaneously hypertensive rats (SHRs). This study was designed to investigate the effects of atorvastatin administered in the early stage on LV remodeling in SHRs, and to explore the underlying mechanisms.Sixteen male 8-week-old SHRs were randomized to receive disti...

journal_title：International heart journal

authors： Zhao XY,Li L,Zhang JY,Liu GQ,Chen YL,Yang PL,Liu RY

更新日期：2010-01-01 00:00:00

abstract：:Sarcoidosis is a systemic granulomatous disorder whose prognosis worsens when the heart is involved, and early diagnosis is important. Endomyocardial biopsy is the most helpful diagnostic examination, but suffers from low sensitivity and low specificity. Microvolt T wave alternans (MVTWA) is utilized in noninvasive ex...

journal_title：International heart journal

authors： Matsumoto S,Hirayama Y,Saitoh H,Ino T,Miyauchi Y,Iwasaki YK,Yasutake M,Seino Y,Atarashi H,Katoh T,Mizuno K

更新日期：2009-11-01 00:00:00

abstract：:Prognosis of patients with heart failure (HF) remains unclear in Japan and should be determined in a prospective fashion. A prospective cohort of The Shinken Database comprised details on all of the new patients, including both inpatients and outpatients, who visited The Cardiovascular Institute Hospital in 2004-2005....

journal_title：International heart journal

authors： Goda A,Yamashita T,Suzuki S,Ohtsuka T,Uejima T,Oikawa Y,Yajima J,Koike A,Nagashima K,Kirigaya H,Sagara K,Ogasawara K,Isobe M,Sawada H,Aizawa T

更新日期：2009-09-01 00:00:00

abstract：:The current study aimed to identify risk factors for atrial fibrillation (AF) detected during routine medical checkups of male workers in Japan. A nested case-control study was conducted using retrospective data from January 1998 to December 2006 collected at a hospital in Ishikawa Prefecture. Cases were those first d...

journal_title：International heart journal

authors： Minami M,Kobayashi Y,Toyokawa S,Inoue K,Takeshita Y

更新日期：2009-07-01 00:00:00

abstract：:Ablation catheters with multiple electrodes are effective for the creation of linear atrial lesions but are associated with an increased risk of coagulum formation. In an animal study, we used a novel 9Fr deflectable ablation catheter with two saline/foam electrode pocket covered with 20 mm tubing. Each pocket contain...

journal_title：International heart journal

authors： Watanabe I,Min N,Okumura Y,Kofune M,Ashino S,Ohkubo K,Nakai T,Kunimoto S,Kasamaki Y,Hirayama A

更新日期：2009-05-01 00:00:00

abstract：:This experimental study investigated the impact of hyperglycemic control on left ventricular (LV) function using a model of diabetes mellitus (DM) (induced by streptozocin 60 mg/kg). Sixteen adult-Sprague Dawley rats were divided into group 1 (poor hyperglycemic control, n = 8) and group 2 (good hyperglycemic control,...

journal_title：International heart journal

authors： Sung PH,Sun CK,Ko SF,Chang LT,Sheu JJ,Lee FY,Wu CJ,Chua S,Yip HK

更新日期：2009-03-01 00:00:00

abstract：:Music therapy (MT) has been used in geriatric nursing hospitals, but there has been no extensive research into whether it actually has beneficial effects on elderly patients with cerebrovascular disease (CVD) and dementia. We investigated the effects of MT on the autonomic nervous system and plasma cytokine and catech...

journal_title：International heart journal

authors： Okada K,Kurita A,Takase B,Otsuka T,Kodani E,Kusama Y,Atarashi H,Mizuno K

更新日期：2009-01-01 00:00:00

abstract：:Implantation of a paclitaxel- or sirolimus-eluting stent (SES) may be associated with endothelial dysfunction. In the present study, we compared coronary endothelial function after zotarolimus-eluting stent (ZES) implantation to that after SES implantation. Patients who had one stent implantation for a single lesion i...

journal_title：International heart journal

authors： Shin DI,Seung KB,Kim PJ,Chang K,Choi JK,Jeon DS,Kim MJ,Lee MY,Chung WS

更新日期：2008-11-01 00:00:00

abstract：:The aim of the present study was to determine if prednisone, a glucocorticoid, added to conventional treatment for patients with decompensated congestive heart failure (DCHF) refractory to the conventional care, results in significant relief of congestive symptoms and improvement of clinical status. Diuretic-based str...

journal_title：International heart journal

authors： Zhang H,Liu C,Ji Z,Liu G,Zhao Q,Ao YG,Wang L,Deng B,Zhen Y,Tian L,Ji L,Liu K

更新日期：2008-09-01 00:00:00

abstract：:Sleep-disordered breathing (SDB) is frequently observed in patients with congestive heart failure. Recent studies have shown that SDB negatively affects the onset of congestive heart failure; however, no studies have addressed the relationship between the level of SDB and the onset time of acute dyspnea. We hypothesiz...

journal_title：International heart journal

authors： Yoneyama K,Osada N,Shimozato T,Ishibashi Y,Hayashi A,Takahashi E,Kida K,Suzuki K,Tamura M,Inoue K,Akashi YJ,Omiya K,Miyake F,Izawa KP,Watanabe S

更新日期：2008-07-01 00:00:00